A Star Cluster Program

Revolutionizing Health through Genomic Engineering and AI

School of Medicine

Imagine a world where we can prevent blindness, cure genetic diseases and decode the genetic foundations of rare conditions. These ambitious goals are within reach thanks to the groundbreaking work of UC Irvine’s researchers and clinicians.


Michael J. Stamos, MD Dean of the School of Medicine

Revolutionizing Health through Genomic Engineering and AI

The GENESIS (Genomic Engineering, Next-Generation Omics and Innovative Solutions) Star Cluster aims to address pressing healthcare challenges through leading-edge research and technology. By recruiting a visionary leader to assemble an interdisciplinary team, we will strive to drive innovations that can transform healthcare.

The GENESIS Star Cluster has the potential to significantly impact the future of healthcare by:

  • Advancing personalized medicine and developing predictive models for early disease detection.
  • Pioneering targeted gene therapies and improving data-driven decision-making.
  • Enhancing patient monitoring and accelerating the transition from discovery to clinical application.

To achieve these transformative goals, we are launching an initiative to hire faculty in the School of Medicine who will lead these research and clinical efforts.

Key Focus Areas

Functional Genomics and Disease Mechanisms: Mapping gene functions, exploring disease pathways and identifying genetic mutations to create targeted therapies.

Transcriptomics and RNA Therapeutics: Understanding RNA mechanisms and developing therapies to correct and regulate gene expression.

Clinical Translation and Gene Therapy: Bridging research and real-world application through innovative gene editing and RNA-targeting therapies.

AI-Driven Multi-Omic Integration and Predictive Therapeutics: Using artificial intelligence and machine learning to analyze complex multi-omics datasets and uncover novel therapeutic targets.

Electronic Health Records Integration: Integrating genomic data with health data systems for a holistic approach to patient care.

Strategic Objectives

The GENESIS Star Cluster aligns with the School of Medicine’s mission: Discover. Teach. Heal.

Discover

Driving Innovative Research: Leveraging genomic data and machine learning to develop predictive models for disease risk, outcomes and treatment strategies.

Advancing Precision Medicine: Creating individualized treatment plans based on unique genetic profiles and clinical histories.

Fostering Collaboration: Encouraging interdisciplinary collaboration to attract diverse funding opportunities and accelerate progress.

Teach

Enhancing Education in Genetics/Genomics: Contributing to the growth of our genetics program, progressing toward a PhD program and providing real-world opportunities for trainees.

Heal

Translating Research into Practice: Accelerating the translation of research findings to improve early disease detection, patient stratification and treatment protocols.

Positioning UC Irvine as a Leader: Strengthening our role at the forefront of biomedical research and precision medicine.

Pioneering Medical Innovations

Through groundbreaking research, we will uncover the genetic codes of inherited diseases and educate the next generation of healthcare professionals and researchers. By integrating advanced technologies, we will translate discoveries into precise diagnostics and targeted treatments to benefit individual patients and address broader public health challenges.

Join Us in Making an Impact

We are seeking philanthropic partners to fund Star Clusters throughout the Susan & Henry Samueli College of Health Sciences. These distinguished recruits will strengthen our research enterprise significantly. By becoming a philanthropic partner, you will forever link your legacy to a Star Cluster and its groundbreaking research. To learn more about supporting this transformative initiative at UC Irvine, please contact Health Advancement at healthadvancement@uci.edu.

UC Irvine Star Clusters


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